How We Calculate Your Estimate
These calculations leverage industry resources and are for illustrative purposes. Result may vary on a case-by-case basis.
Discuss with an ExpertInput Assumption
Evidence Source
30% baseline trial dropout rate of patients
$19,500 Cost to replace a dropped-out patient
$7,829 – Phase I
$23,737 – Phase II
$55,716 – Phase III
Every 10% in patient dropout adds a 45-day replacement delay (30-day screening window plus 15-day coordination and restart)
BNIH/MRCT Templates, ClinicalTrials.gov
This tool does not account for performance variability across sites. In reality, site density acts as a multiplier on baseline patient dropout rates, ranging from 0.92x (very high-density) to 1.10x (very low-density).
Results are based on an internal Medidata analysis applying industry-standard benchmarks and assumptions. This is not a guarantee of specific performance or results. Actual results may vary depending on study complexity, therapeutic area, individual client configurations, and other variables.