How We Calculate Your Estimate

These calculations leverage industry resources and are for illustrative purposes. Result may vary on a case-by-case basis.

Discuss with an Expert
Input Assumption
Evidence Source

30% baseline trial dropout rate of patients


$19,500 Cost to replace a dropped-out patient


$7,829 – Phase I
$23,737 – Phase II
$55,716 – Phase III


Every 10% in patient dropout adds a 45-day replacement delay (30-day screening window plus 15-day coordination and restart)

BNIH/MRCT Templates, ClinicalTrials.gov


This tool does not account for performance variability across sites. In reality, site density acts as a multiplier on baseline patient dropout rates, ranging from 0.92x (very high-density) to 1.10x (very low-density).

Results are based on an internal Medidata analysis applying industry-standard benchmarks and assumptions. This is not a guarantee of specific performance or results. Actual results may vary depending on study complexity, therapeutic area, individual client configurations, and other variables. 

Explore what drives abandonment and how leading teams are improving the patient experience with eCOA.